Source of founding: National Science Centre (NCN), Preludium Program
Duration: July 2017- July 2020
Project No: 2016/23/N/ST8/03692
Project manager/ principal investigator: Piotr Denis
The aim of the project is to obtain polymeric nonwoven using electrospinning method and to characterize its properties. Material will consist of two components. One will be poly(glycerol sebacate), PGS – polyester with elastomeric-like properties, with, hopefully, good elasticity. The second component of nonwovens will be the other biodegradable polymer, from polyesters group. Electrospun materials consisting of popular, biodegradable polyesters usually lack hydrophilicity and elasticity. Addition of PGS to the polymeric system is likely to modify properties of polylactide (PLA) or its copolymer PLGA in a way to make them more appropriate for application within the scope of soft tissues engineering e.g. connective tissue or some muscles. Soft tissues are largely composed of collagen and elastin fibers. Mechanical properties of PGS are similar to native fibrous structures in soft tissues, but reproducibility of PGS using electrospinning method is very complicated. The use of PGS as an additive in bicomponent polymeric system partially bypasses typical problems and it modifies, in a potentially positive way, properties of the so-called carrier material – the second component. To achieve it and to estimate the real potential of such material, elementary research studies are indispensable.